Knee Pain

Knee Pain Research Study Opportunity

Purpose of the Research Study:

We are conducting a research study evaluating an investigational surgical treatment intended to repair knee cartilage damage and ease knee pain. Eligible participants must be between the ages of 18 and 55 & have knee pain caused by knee cartilage damage. The presence of knee cartilage damage is assessed by the study physician at the first visit and involves a set of diagnostic x-rays and an MRI. Qualified participants will receive medical care, including an MRI & knee surgery. This study will evaluate the safety and effectiveness of the Cartilage Autograft Implantation System or CAIS™, which is a surgical treatment for cartilage damage in the knee. CAIS will be compared to a standard surgical treatment called microfracture.

List of diagnostic procedures involved:

• Radiographs (x-rays) of the knee will be done two (2) times over the course of 48 months
• An MRI of the knee will be done seven (7) times over the course of 48 months.

List of surgical procedures involved (if eligible):

• Diagnostic arthroscopy
• There is a 50 % chance of receiving either microfracture (standard surgical treatment) or CAIS (study surgical treatment)

Length of time of commitment to the study:

Your participation is expected to last a minimum of 48 months, which will include 1 visit prior to the surgery, 1 visit for surgery, and at least 11 visits to the physician’s office/clinic to follow-up on your progress.

Investigational Drug or Device:

Cartilage Autograft Implantation System (CAIS)

Compensation:

Participants will be compensated for their time and travel.

Contact:

For more information about enrolling in this study, please visit the study website at www.kneepainstudy.com or contact Cara Fontaine or 212-598-6521 FREE.